News

It is with pleasure that Phytronix Technologies Inc. announces the recruitment of Mr. Alex Birsan as a Research Scientist and LDTD^® Sales & Marketing Specialist. Mr. Birsan' previous work experience in the pharmaceutical field allowed him to acquire the scientific knowledge necessary to promote the LDTD^® technology worldwide. He will provide global sales support in order to better serve our international customers.

Moreover, the recruitment of Mrs. Cynthia Paradis in the  production department of the LDTD^® ionization source will help meet the increasing demand caused by the progression of sales. Mrs. Paradis is well experienced in the field of electronics.

Finally, Phytronix Instruments Inc. announces the recruitment of Mr. Jean-Christophe Pothier as a Research Physicist for the Scientific Instrumentation Services. Mr. Pothier will join our Montreal multidisciplinary team specialised in the service of analytical and scientific laboratory instrumentation.

It is with great pride that we welcome our new employees.

The Direction

On October 1st, 2011, the following article was published on line by the Publication LC GC North America:

Laser Diode Thermal Desorption Tandem Mass Spectrometry for Simultaneous Quantitation of Metformin and Sitagliptin in Mouse and Human Dried Blood Spots

By: John G. Swales, Richard T. Gallagher, Mark Denn, Raimund M. Peter, Nick Duczak LCGC NORTH AMERICA

Integration of LDTD technology into AB SCIEX mass spectrometers

FRAMINGHAM, Mass. - June 6, 2011 - AB Sciex, a global leader in life science analytical technologies, and Phytronix Technologies today announced that they are working together to expand choices for scientists and lab analysts focused on high-throughput pharmaceutical applications, forensic toxicology and food safety testing. The two companies are integrating Phytronix's LDTD (Laser Diode Thermal Desorption) Ion source with the AB SCIEX TripleTOF 5600 System as a first step to offer the high-throughput accurate mass market a better alternative than other technologies.  AB SCIEX and Phytronix are presenting information about LDTD-MS/MS integration at the American Society of Mass Spectrometry (ASMS) conference in Denver this week. 

This joint effort aims to deliver the latest innovation in mass spectrometry in a workflow solution customized for high-throughput applications.  The AB SCIEX TripleTOF 5600 System offers the industry's fastest and most sensitive high-resolution mass spectrometer for high-performance qualitative and quantitative analysis.  Complementing this breakthrough technology is Phytronix's LDTD Ion Source, which is the fastest high throughput solution on the market. 

This development will benefit the entire AB SCIEX mass spectrometry portfolio and is expected to increase the throughput of workflows using the industry's highest sensitivity mass spectrometers, exclusively from AB SCIEX   

Journal of Pharmaceutical and Biomedical Analysis, Volume 53, Issue 3, 2 November 2010, Pages 740-744, John g. Swales, Richard Gallagher and Raimund M. Peter   

Determination of metformin in mouse, rat, dog and human plasma samples by laser diode thermal desorption/atmospheric pressure chemical ionization tandem mass spectrometry

Phytronix Technologies inc. settles down in its new production plant in December 2010. 

Journal of Pharmaceutical and Biomedical Analysis 2010, 54, pp 1088-1095 , Olivier Heudi, Samuel Barteau, Pierre Picard, Patrice Tremblay, Franck Picard, and Olivier Kretz. DOI:10.1016/j.jpba.2010.11.025.

Laser Diode Thermal Desorptino-Positive Mode Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry For The Ultra-Fast Quantification of a Pharmaceutical Compound in Human Plasma

Journal of Pharmaceutical and Biomedical Analysis, Volume 53, Issue 3, 2 November 2010, Pages 740-744, John g. Swales, Richard Gallagher and Raimund M. Peter   

Determination of metformin in mouse, rat, dog and human plasma samples by laser diode thermal desorption/atmospheric pressure chemical ionization tandem mass spectrometry

QUEBEC CITY, Quebec, Canada and MILFORD, Mass. - July 26, 2010 - Phytronix Technologies Inc. and Waters Corporation (NYSE:WAT) announced today they are entering into a collaborative agreement to develop a very high throughput solution based on the Phytronix Laser Diode Thermal Desorption (LDTD^®) Ion Source.  The LDTD Technology combined with a Waters^® MS/MS is geared towards high throughput applications in drug discovery research, toxicology, forensics, food safety and environmental monitoring.

The LDTD Ion Source uses a "shotgun" approach to introduce a sample by a rapid laser thermal desorption process into a Waters MS/MS, ionizing...

Here is the reference of the full article:

Laser Diode Thermal Desorption/Atmospheric Pressure Chemical Ionization Tandem Mass Spectrometry Analysis of Selected Steroid Hormones in Wastewater: Method Optimization and Application

Paul B. Fayad, Michèle Prévost and Sébastien Sauvé

Anal. Chem., 2010, 82 (2), pp 639-645

Publication Date (Web): December 15, 2009 (Article)

DOI: 10.1021/ac902074x

Direct Analysis Mass Spectrometry: Technique and applications, April 21st, 2010.

Phytronix Technologies will assist this meeting at the Alderley Park Conference Centre, AstraZeneca, Alderley Park, Cheshire, UK.

For more information, consult http://www.bmss.org.uk/meetings.htm

Atmospheric pressure chemical ionization-tandem mass spectrometry (APCI-MS/MS) was applied for the first time to the direct analysis of octamethylcyclotetrasiloxane (D4) and decamethylcyclopentasiloxane (D5) in gaseous matrixes without extraction or prior chromatographic separation. Mass spectrometric characteristics of both compounds under APCI conditions and their fragmentation behavior in MS/MS were investigated. Unlike the classical gas chromatography/mass spectrometry (GC/MS), which involves solvent extraction before gas chromatography, the proposed approach prevents contamination from GC system components and provides unambiguous structural assignments. The method performs well achieving good linearity (R² > 0.997), low limits of detection (4-6 μg/m³), good precision (RSD < 10%) and accuracy (>93%), and a wide dynamic range. Its applicability to real-world samples was evaluated through measurements of D4 and D5 concentrations in air and biogas samples. The high sensitivity, selectivity, and reliability of this method render our approach a good alternative to the commonly used GC/MS method.

You can acces the full article at this address:

http://pubs.acs.org/action/doSearch?action=search&author=serge+moore&qsSearchArea=author&type=within&publication=40025958

BASi provides clients with increased sample analysis speed and quick turnaround with the LDTD technology. Fast screening is combined with accurate quantification results, to benefit any bioanalytical studies.

http://www.euroinvestor.fr/news/story.aspx?id=10569352&bw=20090807005046

Phytronix launches its new LDTD-384 plate platform, the unique way for acheiving 1400 samples analysis per hour (sample-to sample run time as low as 2.5 seconds).  Phytronix proves again its leadership in Ultra-High Throughput technology for mass spectrometry by developing a new shotgun approach where the sample is introduced in the mass spectrometer by a fast LASER DIODE THERMAL DESORPTION desorption process and ionized by an atmospheric pressure chemical reactions (LDTD-APCI). No matter what your application field is, the LDTD technology is an unmatched alternative to increase your throughput.

Thermo Fisher Scientific Installs TSQ Quantum^TM Mass Spectrometer
on a Bus for Mobile Environmental Monitoring

The US patent for the LDTD source has been accepted.

Thermo Fisher Scientific Partners with Phytronix Technologies to Offer Ultra High-Speed LDTD Technology for Large Volume LC/MS Analyses

Phytronix Technologies and Thermo Fisher Scientific have signed a distribution agreement.

The US patent for the LDTD source has been accepted.

In collaboration with Merck Frosst Canada Ltd. This paper describes the development of a high-throughput method for the analysis of cytochrome P450 (CYP)

In the Economic and financial profile of Québec, the ministère des Finances of the gouvernment of Québec as presented Phytronix Technologies as a "Québec success story".